Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interfacial titanium oxide between hydroxyapatite and TiAlFe substrate.

Valentin Nelea1, Constantin Morosanu, Mircea Bercu

  • 1National Institute for Lasers, Plasma, and Radiation Physics, PO Box MG-54, Bucharest 77125, Romania.

Journal of Materials Science. Materials in Medicine
|June 15, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inositol Thiophosphates as Inhibitors of Mammalian, Plant, and Fungal Phytases.

ACS chemical biology·2026
Same author

Fibrillin-1 Inhibits Early Adipogenic Commitment Via αvβ3 Integrin Signaling.

Journal of molecular biology·2026
Same author

Correction: Mahmood et al. Laser Melting Deposition Additive Manufacturing of Ti6Al4V Biomedical Alloy: Mesoscopic In-Situ Flow Field Mapping via Computational Fluid Dynamics and Analytical Modelling with Empirical Testing. <i>Materials</i> 2021, <i>14,</i> 7749.

Materials (Basel, Switzerland)·2026
Same author

Optimised amine density via plasma treatment for covalent immobilisation of AMPs to promote osteoblasts and enhance antimicrobial activity.

Colloids and surfaces. B, Biointerfaces·2025
Same author

Impact of N-linked glycans on the dual short fibulin/LTBP-4 axes regulating elastogenesis.

The FEBS journal·2025
Same author

Bone mineral tessellation: Atomic force microscopy of the volume-filling mineralization pattern in hydrated and dehydrated states.

Acta biomaterialia·2025
Same journal

Zinc-polydopamine nanozyme promotes mitochondrial biogenesis and alleviates inflammation and muscle atrophy during the perioperative period of surgery.

Journal of materials science. Materials in medicine·2026
Same journal

Immuno-instructive biomaterials for coronary artery disease and myocardial infarction repair.

Journal of materials science. Materials in medicine·2026
Same journal

Effect of topical nanoemulsion of minoxidil on animal hair growth: an in vivo study.

Journal of materials science. Materials in medicine·2026
Same journal

Selective cytotoxicity of zinc peroxide and tetrapodal zinc oxide micro-nanoparticles against breast cancer cells: synthesis, characterization, and therapeutic potential.

Journal of materials science. Materials in medicine·2026
Same journal

Progress and challenges of tantalum-containing biomaterials in regenerative medicine applications.

Journal of materials science. Materials in medicine·2026
Same journal

Synchronizing degradation with regeneration: a model-driven framework for designing biodegradable biomaterials in bone tissue engineering.

Journal of materials science. Materials in medicine·2026
See all related articles

This study investigated hydroxyapatite (HA) thin films on titanium alloy, revealing that titanium oxide interfacial layers form during annealing. Inserting a titanium nitride (TiN) buffer layer effectively inhibited this oxide formation, impacting film properties.

Area of Science:

  • Biomaterials science
  • Materials science
  • Surface science

Background:

  • Hydroxyapatite (HA) coatings are crucial for biomedical implants.
  • Titanium alloys are common implant substrates.
  • Understanding the HA-titanium interface is vital for implant osseointegration and longevity.

Purpose of the Study:

  • To characterize the interface between nano-crystalline HA thin films and Ti5Al2.5Fe alloy.
  • To investigate the effect of deposition conditions and post-treatments on interface development.
  • To evaluate the influence of an interfacial titanium oxide layer on HA film properties.

Main Methods:

  • Radio-frequency magnetron sputtering for HA thin film deposition.
  • Grazing incidence X-ray diffraction and Fourier transform infrared spectrophotometry for structural analysis.

Related Experiment Videos

  • Nanoindentation for mechanical property assessment.
  • Main Results:

    • Annealing in humid air promoted TiO(2) growth at the HA/Ti alloy interface.
    • Direct sputtering at high temperatures led to TiO(2) diffusion into HA films.
    • A crystalline TiN buffer interlayer successfully inhibited interfacial TiO(2) formation.
    • Mechanical properties of HA films were affected by interfacial layer development.

    Conclusions:

    • The formation of interfacial titanium oxide layers can be controlled by deposition and annealing parameters.
    • TiN buffer interlayers offer a strategy to prevent detrimental interfacial reactions.
    • Controlling the HA/Ti interface is essential for optimizing the performance of biomedical implants.