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Related Concept Videos

Sperm Structure and Semen Composition01:22

Sperm Structure and Semen Composition

During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...

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Related Experiment Video

Updated: Jul 14, 2026

The Examination of Peroxidase-Positive Leukocytes in Semen
04:36

The Examination of Peroxidase-Positive Leukocytes in Semen

Published on: January 19, 2024

[Evaluation of antioxidant system in normal semen].

Juan M Gallardo1

  • 1Unidad de Investigación Médica en Enfermedades Nefrológicas, UMAE-Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS. jmgallardo@salud.gob.mx

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
|June 16, 2007
PubMed
Summary

Reactive oxygen species (ROS) can damage sperm. Measuring antioxidants like superoxide dismutase (SOD) and glutathione peroxidase (GPx), along with oxidative markers malondialdehyde (MDA) and nitric oxide (NOx), can help evaluate male infertility.

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Evaluation of Intracellular Location of Reactive Oxygen Species in Solea Senegalensis Spermatozoa
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Evaluation of Intracellular Location of Reactive Oxygen Species in Solea Senegalensis Spermatozoa

Published on: March 11, 2018

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Last Updated: Jul 14, 2026

The Examination of Peroxidase-Positive Leukocytes in Semen
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The Examination of Peroxidase-Positive Leukocytes in Semen

Published on: January 19, 2024

Evaluation of Intracellular Location of Reactive Oxygen Species in Solea Senegalensis Spermatozoa
10:24

Evaluation of Intracellular Location of Reactive Oxygen Species in Solea Senegalensis Spermatozoa

Published on: March 11, 2018

Area of Science:

  • Reproductive biology and oxidative stress research.
  • Biochemistry of seminal fluid and spermatozoa.
  • Human male reproductive health.

Context:

  • Reactive oxygen species (ROS) can cause irreversible damage to sperm function.
  • Antioxidative mechanisms are crucial for protecting sperm from oxidative damage.
  • Understanding oxidative-antioxidative balance is key in male reproductive health.

Purpose:

  • To establish normal reference ranges for key oxidative and antioxidative markers in healthy human seminal fluid.
  • To quantify concentrations of superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA), and nitric oxide (NOx).
  • To investigate the distribution of these markers in both seminal fluid and spermatozoa.

Summary:

  • This study measured SOD, GPx, MDA, and NOx in semen from 45 healthy men.
  • SOD and MDA levels were similar in seminal fluid and spermatozoa.
  • GPx and NOx concentrations were significantly higher in spermatozoa compared to seminal fluid.

Impact:

  • Provides normative data for essential oxidative and antioxidative markers in human seminal fluid.
  • Suggests that measuring these markers can aid in diagnosing male infertility, especially when traditional semen analysis is normal.
  • Highlights the differential distribution of antioxidants within the seminal compartment, offering insights into sperm protection mechanisms.