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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...

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Related Experiment Video

Updated: Jul 14, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Rhinophymatous amelanotic melanoma.

Jennifer Peterson1, Milton Rowley

  • 1Texas Tech University, Department of Dermatology, Lubbock, USA. jdd4920@hotmail.com

Cutis
|June 16, 2007
PubMed
Summary

Amelanotic melanoma can mimic other skin conditions, leading to delayed diagnosis. This case highlights an unusual presentation resembling rhinophyma, emphasizing the need for vigilance in diagnosing this rare melanoma subtype.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Amelanotic melanoma is a rare variant of melanoma lacking pigment.
  • It frequently mimics benign or malignant skin lesions, complicating diagnosis.

Observation:

  • A case of amelanotic melanoma presented with clinical features indistinguishable from rhinophyma.
  • Rhinophyma is a benign sebaceous gland hyperplasia of the nose.

Findings:

  • The amelanotic melanoma successfully mimicked the appearance of rhinophyma.
  • Delayed diagnosis is a common challenge with amelanotic melanoma.

Implications:

  • This case underscores the importance of considering amelanotic melanoma in the differential diagnosis of lesions resembling rhinophyma.
  • Increased awareness and diagnostic vigilance are crucial for timely treatment of amelanotic melanoma.

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