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An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
Published on: May 13, 2020
Mutagenicity of filtrates from respirable coal fly ash
C E Chrisp1, G L Fisher, J E Lammert
1Radiobiology Laboratory, University of California, Davis, CA 95616, USA.
Abstract:
Incubation of histidine-requiring auxotrophs of the bacterium Salmonella typhimurium with cyclohexane-, saline-, and serum-soluble surface components of respirable fly ash particles produced an increased number of revertants in two frameshift tester strains. The results are consistent with the hypothesis that both organic and inorganic mutagens are present in coal fly ash.

