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Updated: Jul 9, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

Thyroid gangliosides with high affinity for thyrotropin: potential role in thyroid regulation

B R Mullin1, T Pacuszka, G Lee

  • 1Laboratory of Biochemical Pharmacology, National Institute of Arthritis, Metabolism, and Digestive Diseases, Bethesda, MD 20014, USA.

Science (New York, N.Y.)
|January 6, 1978
PubMed
Summary

Thyroid cell membranes contain gangliosides that inhibit thyrotropin binding. A novel ganglioside, present in trace amounts, is the most potent inhibitor, suggesting a role in hormone signaling.

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