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Related Experiment Videos

[Mydriasis caused by plant contact].

H Wilhelm1, B Wilhelm, U Schiefer

  • 1Abteilung für Pathophysiologie, Universitäts-Augenklinik, Tübingen, Bundesrepublik Deutschland.

Fortschritte Der Ophthalmologie : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|January 1, 1991
PubMed
Summary

Plant alkaloids, like scopolamine from Datura species, can cause dilated, non-reactive pupils. This mimics serious neuro-ophthalmological conditions, necessitating careful diagnosis to rule out other causes.

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Area of Science:

  • Ophthalmology
  • Toxicology
  • Botany

Context:

  • Plant-induced mydriasis can mimic neuro-ophthalmological disorders.
  • Alkaloids from plants like Datura species are common culprits.
  • Accidental ocular exposure during plant maintenance is a frequent cause.

Purpose:

  • To identify plant-induced mydriasis as a differential diagnosis for non-light-reactive pupils.
  • To highlight the role of specific plant alkaloids (scopolamine, atropine) in causing mydriasis.
  • To emphasize the importance of excluding other causes before pilocarpine testing.

Summary:

  • Uni- or bilateral mydriasis unresponsive to light and pilocarpine may result from contact with alkaloid-containing plants.
  • Datura species (e.g., Datura suaveolens) are common sources in Germany, containing significant scopolamine.
  • Plant parts, especially during pruning, can contaminate the eye, leading to pupil dilation.

Impact:

  • Raises awareness among clinicians about plant-induced mydriasis.
  • Aids in the differential diagnosis of dilated, non-reactive pupils.
  • Informs the public about potential ocular toxicity from common ornamental plants.

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