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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided

Christine M Richardson1, Claire L Nunns, Douglas S Williamson

  • 1Vernalis (R&D) Ltd, Granta Park, Cambridge CB21 6GB, UK. c.richardson@vernalis.com

Bioorganic & Medicinal Chemistry Letters
|June 16, 2007
PubMed

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