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Stroke mortality and race: does access to care influence outcomes?
Masoor Kamalesh1, Jianzhao Shen, William M Tierney
1Roudebush VA Medical Center and Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA. Masoor.kamalesh@med.va.gov
Insights
African-Americans (AA) had lower mortality rates after ischemic stroke discharge in VA hospitals compared to white patients. This finding contrasts with non-VA studies and suggests VA care may improve stroke outcomes for AA.
Area of Science:
- Neurology
- Public Health
- Health Services Research
Background:
- Stroke is a leading cause of death in the U.S.
- Racial disparities in stroke mortality exist.
- Previous studies reported higher stroke mortality in African-Americans (AA) in non-VA settings.
Purpose of the Study:
- To investigate racial differences in post-discharge mortality after ischemic stroke.
- To determine if Veterans Health Administration (VHA) care access influences stroke mortality rates in AA.
- To test the hypothesis that VA care mitigates excess stroke mortality in AA.
Main Methods:
- Analysis of VHA administrative data for ischemic stroke patients discharged between 1990-1997.
- Inclusion of demographic, clinical, and mortality data.
- Calculation of Charlson comorbidity index and 1-year survival analysis.
Main Results:
- Study included 55,094 VHA stroke patients (63% white, 21% AA).
- Charlson comorbidity index was similar between racial groups.
- One-year mortality was higher for white patients (HR 1.06; 95% CI 1.02-1.10), with survival rates of 0.86 for whites vs. 0.87 for AA.
Conclusions:
- AA patients experienced marginally lower mortality rates post-discharge from VA hospitals after ischemic stroke.
- This outcome contrasts with findings from non-VA hospitals.
- Access to VHA care may play a role in reducing stroke-related deaths in AA.
Background:
Stroke is the third leading cause of death in the United States. We investigated racial differences in death after hospital discharge for ischemic stroke in a large cohort of Veterans Health Affairs (VHA) stroke patients. We hypothesized that having access to VA care would ameliorate the excess stroke mortality rates in African-Americans (AA) reported in non-VA studies.
Methods:
Hospital administrative data were used to identify all patients discharged from any VA hospital between October 1990 and September 1997 with a primary discharge diagnosis of ischemic stroke (ICD-9-CM codes 434 and 436). We obtained demographic data and clinical data recorded during the index hospitalization and after discharge, including deaths, from VA clinical and administrative databases. The Charlson comorbidity index was constructed for each patient from the index admission's discharge diagnoses. Patients were followed through 1998.
Results:
Of 55,094 VHA stroke patients discharged after ischemic strokes, 34,579 (63%) were white and 11,530 (21%) were AA. Charlson index was similar between the groups. One-year mortality rate was significantly higher for whites: Adjusting for demographic and clinical differences, being white remained predictive of higher mortality rates (multivariable hazard ratio, 1.06; 95% CI, 1.02 to 1.10). From Kaplan-Meier estimates, the probability that whites would survive for 1 year was 0.86 compared with 0.87 for AA.
Conclusions:
Despite having similar severity of illness and adjusting for other clinical differences, mortality rate was marginally lower in AA after being discharged from VA hospitals after ischemic strokes. This is contrary to prior reports from non-VA hospitals and suggests the possibility of access to care playing a role in stroke deaths.
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