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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
[Mortality after acute coronary syndrome].
Kaes Al-Anee1, Ahmed Al-Ani, Magne Henriksen
1Sykehuset Østfold Moss, 1535 Moss.
Summary
This study on acute coronary syndrome found a 17.5% six-month mortality rate, which is higher than in clinical trials but similar to recent NSTEMI reports. Early PCI showed no deaths in STEMI patients.
Area of Science:
- Cardiology
- Internal Medicine
- Public Health
Background:
- Acute coronary syndrome (ACS) is a leading cause of hospitalization, necessitating effective interventions.
- Limited follow-up data exists for ACS patients in Norwegian local hospitals.
- This study addresses the need for local data on ACS outcomes.
Purpose of the Study:
- To evaluate the outcomes and mortality rates of patients with acute coronary syndrome in a local hospital setting.
- To provide follow-up data on ACS patients, stratified by STEMI, NSTEMI, and UAP.
- To compare local findings with existing national and international data.
Main Methods:
- Retrospective and prospective cohort study of 206 ACS patients from a local hospital.
- Classification of patients into ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina pectoris (UAP).
- Review of medical records, ECGs, and 6-month follow-up data for surviving patients.
Main Results:
- Overall 6-month mortality was 17.5% (STEMI: 14%, NSTEMI: 23%, UAP: 3%).
- Mean age at onset was 67 for STEMI and 76 for NSTEMI.
- No deaths were observed in STEMI patients receiving primary PCI within 12 hours of symptom onset.
Conclusions:
- Mortality in this ACS cohort exceeded rates reported in randomized trials.
- Observed mortality rates were comparable to recent reports for NSTEMI.
- Early primary PCI in STEMI patients appears to be associated with favorable outcomes.
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