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Pediatric nephrolithiasis: does treatment affect renal growth?
Karen Reisiger1, Itay Vardi, Yan Yan
1Division of Urology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Urology
|June 19, 2007
Summary
Pediatric kidney stone treatments like shock wave lithotripsy, ureteroscopy, and percutaneous nephrolithotomy do not negatively impact long-term renal growth. This study found no significant differences in kidney growth rates across treatment groups and controls.
Area of Science:
- Pediatric Urology
- Nephrology
- Medical Imaging
Background:
- Long-term effects of pediatric urolithiasis treatments on renal growth are not well-established.
- Limited data exists on renal growth following shock wave lithotripsy, ureteroscopy, and percutaneous nephrolithotomy in children.
Purpose of the Study:
- To investigate the long-term impact of urolithiasis and its treatments on pediatric renal growth.
- To compare renal growth in children treated with shock wave lithotripsy, ureteroscopy, or percutaneous nephrolithotomy versus those receiving no intervention.
Main Methods:
- A cohort of 165 children treated for urolithiasis was retrospectively analyzed, with 74 available for long-term follow-up.
- Renal length was measured via ultrasonography and compared to expected growth using Chen's nomogram.
- Paired data analysis was used to compare observed and predicted renal growth rates across treatment groups.
Main Results:
- No statistically significant differences were observed in renal growth rates between treated and non-treated sides.
- Analysis included children undergoing shock wave lithotripsy, ureteroscopy, percutaneous nephrolithotomy, and a control group.
- Mean follow-up was 6.2 years, with a mean age at treatment of 9 years.
Conclusions:
- Pediatric shock wave lithotripsy, ureteroscopic stone extraction, and percutaneous nephrolithotomy do not appear to impair renal growth.
- Current minimally invasive treatments for pediatric kidney stones are safe concerning long-term renal development.
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