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Protective effect of cyproheptadine in a gerbil model of cerebral ischemia
C Caponnetto1, M Del Sette, M Furlan
1Clinica Neurologica dell'Università di Genova.
Italian Journal of Neurological Sciences
|June 1, 1991
Abstract:
The efficacy of Cyproheptadine, a serotonin antagonist, in preventing the cerebral ischemic damage was tested on experimental model of transient global cerebral ischemia in Mongolian Gerbil. The semi-quantitative histological evaluation of the severity of ischemic damage showed a protective effect of Cyproheptadine, mainly in the anterior cortical areas.