Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Core temperature "null zone".

I B Mekjavić1, C J Sundberg, D Linnarsson

  • 1Department of Physiology, Karolinska Institute, Stockholm, Sweden.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In pursuit of the unicorn.

Experimental physiology·2020
Same author

PlanHab Study: Consequences of combined normobaric hypoxia and bed rest on adenosine kinetics.

Scientific reports·2018
Same author

Optitrain: a randomised controlled exercise trial for women with breast cancer undergoing chemotherapy.

BMC cancer·2017
Same author

Centrifugation as a countermeasure during bed rest and dry immersion: What has been learned?

Journal of musculoskeletal & neuronal interactions·2016
Same author

Effects of five days of bed rest with intermittent centrifugation on neurovestibular function.

Journal of musculoskeletal & neuronal interactions·2015
Same author

Musculoskeletal effects of 5 days of bed rest with and without locomotion replacement training.

European journal of applied physiology·2014
Same journal

Intracranial vasomotor and blood flow responses to light intensity aerobic exercise in young adults: a 4D flow MRI study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Comparative assessments of the COSMED adaptive mixing chamber vs. breath-by-breath methods for oxygen uptake measurements in recreationally active adults.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Can we assess exercise metabolism from skin? Metabolomic profiles in skin dialysate collected during exercise.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Characterization of intracranial pressure variations in ventricular and subarachnoid spaces of the rat brain.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Biomedical Research in an Age of Anxiety: Four Papers for Worried Minds.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Training status augments mechanisms of rapid‑onset vasodilation in healthy young adults.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
See all related articles

Human core temperature regulation involves a distinct neutral zone, not a single set point. Sweating cessation and shivering onset occur at significantly different core temperatures, indicating a wider thermoregulatory range.

Area of Science:

  • Human Physiology
  • Thermoregulation
  • Exercise Science

Background:

  • Understanding human core temperature regulation is crucial for optimizing performance and safety during physical activity.
  • Existing models propose either a precise 'set point' or a 'neutral zone' for core temperature control.
  • Investigating the thresholds for sweating and shivering provides insight into the dynamic range of thermoregulation.

Purpose of the Study:

  • To determine if human core temperature is regulated by a single set point or a neutral zone.
  • To identify the specific core temperatures at which sweating ceases and shivering begins during recovery from exercise.

Main Methods:

  • Nine male subjects performed underwater cycling exercise at 50% maximal work rate.
  • Core temperature was continuously monitored using esophageal (Tes) and rectal (Tre) probes.

Related Experiment Videos

  • Forehead sweat rate (Esw) and oxygen uptake (VO2) were measured throughout exercise and a 100-minute recovery period in 28°C water.

    • Main Results:

    • Sweating ceased at a mean core temperature of approximately 37.4°C (Tes and Tre).
    • Shivering onset, indicated by increased VO2, occurred at a significantly lower mean core temperature of approximately 36.8°C (Tes and Tre).
    • A significant difference (P < 0.001) was observed between the core temperatures for sweating cessation and shivering onset.

    Conclusions:

    • Human core temperature is regulated within a neutral zone, characterized by distinct thresholds for sweating and shivering.
    • The findings challenge the concept of a single core temperature set point for thermoregulation.
    • This neutral zone provides a wider range for physiological responses to thermal challenges during and after exercise.