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Updated: Jul 14, 2026
05:22
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
[Floppy-iris syndrome associated with tamsulosin. A prospective case-control study]
A Bidaguren1, C Irigoyen, J Mendicute
1Hospital Donostia, San Sebastián, Guipúzcoa, España. aritzbidaguren@kaixo.com
Archivos De La Sociedad Espanola De Oftalmologia
|June 19, 2007
Summary
Tamsulosin use is linked to a high incidence of intraoperative floppy-iris syndrome (67%), with reduced pupil reactivity post-surgery. However, complication rates were similar between tamsulosin patients and controls.
Area of Science:
- Ophthalmology
- Surgical Complications
Background:
- Tamsulosin is commonly prescribed for benign prostatic hyperplasia.
- Intraoperative floppy-iris syndrome (IFIS) is a known complication during cataract surgery in patients taking alpha-1 blockers.
Purpose of the Study:
- To determine the incidence of IFIS in patients using tamsulosin.
- To compare intraoperative and postoperative complications between tamsulosin users and a control group.
- To analyze pupillary modifications and endothelial cell loss associated with tamsulosin.
Main Methods:
- Prospective study of 38 male patients undergoing cataract surgery.
- Group 1: 19 patients taking tamsulosin (cases).
- Group 2: 19 patients not taking tamsulosin (controls).
Main Results:
- IFIS features were observed in 67% of tamsulosin patients.
- Iris billowing occurred in 10.5% of tamsulosin patients.
- No IFIS features were noted in the control group; complication rates were similar between groups.
Conclusions:
- Tamsulosin is associated with a high incidence of IFIS.
- A significant finding was reduced pupil reactivity post-surgery in tamsulosin users.
- The study highlights the importance of recognizing IFIS risk factors in cataract surgery patients.
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