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Updated: Jul 14, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy]
1Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. noebg76@hotmail.com
Objective:
To ascertain the efficacy of idebenone and multivitamin treatment in Leber's hereditary optic neuropathy (LHON).
Method:
Two patients diagnosed of unilateral LHON were treated with megadoses of idebenone, vitamin C and riboflavin for one year. They were examined clinically before, during and after treatment.
Results:
No improvement of visual function was observed. Despite the idebenone treatment, in both cases the second eye became involved.
Conclusions:
Despite previous reports of visual recovery with idebenone in patients with LHON, our experience shows that an effective treatment for Leber's disease remains to be found.
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