Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Nelson's syndrome management: current knowledge].

C Garcia¹, L Bordier, C Garcia-Hejl

¹Service d'endocrinologie, hôpital d'instruction des armées Bégin, 69, avenue de Paris, 94160 Saint-Mandé, France. cygarcia@wanadoo.fr

La Revue De Medecine Interne

|June 19, 2007

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evolution in geriatric syndromes and association with survival over 5 years in the GERODIAB cohort of older French diabetic patients.

European geriatric medicine·2020

Same author

Glucocentric risk factors for macrovascular complications in diabetes: Glucose 'legacy' and 'variability'-what we see, know and try to comprehend.

Diabetes & metabolism·2019

Same author

Haemoglobin A1c and 5-year all-cause mortality in French type 2 diabetic patients aged 70 years and older: The GERODIAB observational cohort.

Diabetes & metabolism·2018

Same author

Relationship between achieved personalized glycaemic targets and monitoring of clinical events in elderly diabetic patients.

Diabetes & metabolism·2016

Same author

Predicting factors of hypoglycaemia in elderly type 2 diabetes patients: Contributions of the GERODIAB study.

Diabetes & metabolism·2015

Same author

[Diabetes mellitus in the elderly: from the epidemiological challenge to a personalized approach].

Revue medicale de Liege·2014

Same journal

[Abdominal pain, fever and arthralgia in a 49-year-old woman].

La Revue de medecine interne·2026

Same journal

[Cardiorespiratory functional disorders: A transnosologic approach].

La Revue de medecine interne·2026

Same journal

[Diagnostic evaluation for suspected polycythemia].

La Revue de medecine interne·2026

Same journal

Heart involvements in systemic sclerosis beyond pulmonary hypertension: From conduction, rhythm and function defects to coronary artery disease.

La Revue de medecine interne·2026

Same journal

[Acute intermittent porphyria: When diagnostic errance jeopardizes patient health].

La Revue de medecine interne·2026

Same journal

Autosomal dominant polycystic kidney disease: Current perspectives in 2026.

La Revue de medecine interne·2026

See all related articles

Nelson's syndrome, a complication of Cushing's disease treatment, presents management challenges. Cabergoline shows promise, and analyzing tumor receptors may reveal new therapeutic targets.

Area of Science:

Endocrinology
Oncology

Context:

Nelson's syndrome is a severe complication following bilateral adrenalectomy for Cushing's disease.
Management of Nelson's syndrome remains challenging due to limited therapeutic options.

Purpose:

To review current therapeutic strategies for Nelson's syndrome.
To discuss the long-term observation of a patient with severe Nelson's syndrome.
To explore novel therapeutic targets and agents.

Summary:

Cabergoline, a dopamine agonist, demonstrated efficacy at 2 mg/week over 3.5 years in a severe Nelson's syndrome case.
Somatostatin analogs show potential therapeutic interest.
Conventional treatments like valproic acid and cyproheptadine have variable efficacy.

Related Experiment Videos

Impact:

Cabergoline offers a promising treatment avenue for Nelson's syndrome.
Identifying tumor receptor profiles could lead to personalized therapeutic strategies.
Further research into novel molecules and therapeutic targets is crucial for improving patient outcomes.