Related Experiment Video
Updated: Jul 14, 2026

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy
Published on: May 16, 2015
[Refractory hypoxemia treated early by HFO in a severe traumatic brain injury patient]
1Pôle anesthésie réanimation Samu, CHU de la Cavale-Blanche, Brest, France. lorennb@yahoo.fr <lorennb@yahoo.fr>
Abstract:
A 23-year-old man without previous medical history, was transferred to our surgical intensive care unit for management of a traumatic brain injury (Glasgow Coma Score of 3 on admission). He rapidly presented a refractory hypoxaemia essentially due to posterior alveolar collapse. Severe hypoxaemia and hypercarboxaemia didn't respond to conventional ventilation and complicated the management of the brain injury and the control of intracranial pressure. The introduction of high-frequency oscillatory ventilation permitted a respiratory improvement in 48 hours and a good neurological outcome.
Related Concept Videos
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-IV
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Acute Respiratory Failure-I
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Acute Respiratory Failure-III
