Inhibin and gonadotrophin secretion in physically active males after acute exercise

Serum concentrations of luteinizing hormone (LH) follicle stimulating hormone (FSH), testosterone and inhibin were measured in six physically active male volunteers after heavy exercise on a treadmill. Hormone measurements were made before exercise, immediately after exercise and at 30-min intervals for 3 h after exercise. Serum concentrations of LH fell after exercise reaching nadir values between 60 and 180 min post-exercise. The nadir value of LH for the group as a whole occurred 90 min after exercise. Serum testosterone concentrations paralleled the changes in LH concentrations. Serum FSH and inhibin concentrations did not show any appreciable change from baseline values. The data suggest that acute exercise does not significantly lower serum concentrations of FSH or inhibin. Whether repetitive and prolonged heavy exercise, as in competitive runners, produces alterations in serum inhibin concentrations remains to be determined.