Related Experiment Videos
Results of IVF from a prospective multicentre study.
G Haan1, R E Bernardus, J M Hollanders
1Institute for Medical Technology Assessment, University of Limburg, Maastricht, The Netherlands.
Human Reproduction (Oxford, England)
|July 1, 1991
Summary
This study evaluated in-vitro fertilization (IVF) medical outcomes, finding a 10% success rate per treatment cycle. Approximately one in three to four couples achieved success after multiple IVF attempts, with results varying by patient and hospital factors.
Area of Science:
- Reproductive Medicine
- Health Services Research
Background:
- In-vitro fertilization (IVF) is a key treatment for infertility.
- Evaluating the medical effectiveness of IVF is crucial for cost-effectiveness analyses.
- Understanding factors influencing IVF success rates is essential for patient counseling and resource allocation.
Purpose of the Study:
- To assess the medical outcomes of IVF treatments.
- To identify factors contributing to variations in IVF success rates.
Main Methods:
- Prospective data collection from over 3000 IVF treatments across five Dutch hospitals over two years.
- Analysis of 'take-home baby rate' and clinical pregnancy rates.
- Multivariate logistic regression analysis to identify significant factors.
Main Results:
- The average 'take-home baby rate' per started IVF treatment was 10%.
- The average clinical pregnancy rate per embryo transfer was 20%.
- Success rates varied significantly between patients, treatment episodes, and hospitals, even after multivariate analysis.
Conclusions:
- IVF treatment success is influenced by patient characteristics, treatment specifics, and the treating hospital.
- These identified factors contribute to the variability in IVF outcomes observed in clinical practice.