Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Group G streptococcal lymphadenitis in rats.

B F Corning1, J C Murphy, J G Fox

  • 1Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge 02139.

Journal of Clinical Microbiology
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cost benefit for assessment of intermediate coronary stenosis with fractional flow reserve in public and private sectors in australia.

Heart, lung & circulation·2014
Same author

Optical coherence tomography (OCT) as an adjunct to percutaneous coronary intervention; a single centre experience.

International journal of cardiology·2012
Same author

An incidental finding or an unusual cause for a transient ischaemic attack?

QJM : monthly journal of the Association of Physicians·2011
Same author

Effect of 3-D heat flow near edges in photothermal measurements.

Applied optics·2010
Same author

Comparison of the effects of massive blood transfusions and of liver extract in pernicious anemia.

The Journal of clinical investigation·2010
Same author

ST elevation on the exercise ECG in patients presenting with chest pain and no prior history of myocardial infarction.

Heart (British Cardiac Society)·2009
Same journal

Ebola laboratory preparedness at frontline hospitals: can we or can't we?

Journal of clinical microbiology·2026
Same journal

Reporting macrolide-resistant <i>Mycoplasma pneumoniae</i>: a diagnostic obligation?

Journal of clinical microbiology·2026
Same journal

Diagnostic value of HHV-6A/B genotyping in immunocompromised adults.

Journal of clinical microbiology·2026
Same journal

Multicenter performance evaluation of the Simplexa <i>C. auris</i> Direct assay for the detection of <i>Candida auris</i> colonization in bilateral axilla/groin swabs.

Journal of clinical microbiology·2026
Same journal

Comparison of blood culture contamination rates with standard practice versus two blood diversion devices at a single institution.

Journal of clinical microbiology·2026
Same journal

Risk assessment and mitigation of hepatitis C virus RNA carryover contamination in a reflex testing algorithm.

Journal of clinical microbiology·2026
See all related articles

Group G streptococci, common in humans, caused disease in rats after chemical exposure. This study reports the first natural occurrence of group G streptococcal disease in rats.

Area of Science:

  • Microbiology
  • Veterinary Pathology
  • Toxicology

Background:

  • Group G streptococci are normal flora in humans and can cause various diseases.
  • The oral flora of rats can harbor streptococci, but naturally occurring disease is not well-documented.

Purpose of the Study:

  • To investigate the cause of illness in rats following oral gavage with 7,12-dimethylbenz[a]anthracene.
  • To identify the etiological agent responsible for cervical swelling and lymph node inflammation in rats.

Main Methods:

  • Induction of disease in rats using 7,12-dimethylbenz[a]anthracene.
  • Bacteriological culture and identification of isolates from affected rats.
  • Biochemical and serologic characterization of streptococcal isolates.
  • Histopathologic examination of affected tissues.

Related Experiment Videos

Main Results:

  • Oral gavage with 7,12-dimethylbenz[a]anthracene induced cervical swelling and edema in rats.
  • Pure cultures of beta-hemolytic, group G streptococci were isolated from the cervical lymph nodes of sick rats.
  • Biochemical tests confirmed the isolates as group G streptococci, negative for specific viral pathogens.
  • Histopathology revealed acute necrotizing lymphadenitis with bacterial colonies.

Conclusions:

  • This is the first report of naturally occurring disease caused by group G streptococci in rats.
  • Chemical carcinogen exposure may predispose rats to streptococcal infections.
  • Group G streptococci should be considered in the differential diagnosis of cervical lymphadenitis in rats.