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Updated: Jul 14, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
Ultrafast energy delocalization and electron transfer dynamics in 2-aminopurine-containing trinucleotides
Qiang Wang1, Milen Raytchev, Torsten Fiebig
1Eugene F. Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA.
Abstract:
The fate of electronically excited states in DNA base stacks is of tremendous importance for subsequent photochemical damage reactions in the genome. In this study we present a femtosecond broadband pump-probe study on the adenine isomer 2-aminopurine (Ap) incorporated into trinucleotides. After selective excitation of Ap we can monitor energy delocalization between neighboring Ap moieties as well as excited state electron transfer, depending on the sequence of the trinucleotide. Our results establish the time scale for intrastand excimer formation and reveal the lifetime of the excimer state.
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