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Updated: Jul 14, 2026
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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
Compressive osseointegration promotes viable bone at the endoprosthetic interface: retrieval study of Compress
M J Kramer1, B J Tanner, A E Horvai
1Orthopaedic Oncology Service, UCSF Comprehensive Cancer Center, San Francisco, CA 94115-1939, USA.
International Orthopaedics
|June 20, 2007
Summary
The Compress implant uses high compressive forces for stable bone fixation, avoiding complications like aseptic loosening. Histological analysis revealed new bone formation, indicating a viable bone response.
Area of Science:
- Orthopedic Surgery
- Biomaterials Science
- Bone Biology
Background:
- Conventional stemmed megaprostheses can lead to aseptic loosening due to stress shielding and particle-induced osteolysis.
- The Compress implant utilizes compressive forces for enhanced bone-implant fixation, aiming to mitigate these long-term complications.
Purpose of the Study:
- To evaluate the in vivo biological effects of the high compressive forces generated by the Compress implant.
- To assess the bone-implant interface response in patients receiving the Compress implant for revision surgery.
Main Methods:
- Retrospective review of twelve consecutive patients undergoing revision surgery with the Compress implant.
- Analysis of radiographic and histological evidence from retrieved implant specimens.
- Compressive forces applied ranged from 400-800 lb, with an average implantation duration of 3.3 years.
Main Results:
- No radiographic evidence of prosthetic failure was observed in the majority of patients.
- Two cases of infection were associated with loosening at the bone-prosthetic interface.
- Histological examination showed no evidence of osteonecrosis; instead, new woven bone formation was consistently observed.
Conclusions:
- The Compress implant demonstrates a viable bone response and avoids osteonecrosis, despite high compressive forces.
- The implant design shows potential for stable long-term fixation, particularly in the absence of infection.
- Further research is warranted to optimize implant performance and patient selection for revision arthroplasty.
