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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome

Panagiotis Tsirigotis1, George Mantzios, Vassiliki Pappa

  • 12nd Department of Internal Medicine, Propaudeutic, University of Athens, ATTIKON General University Hospital, Athens, Greece. tsiris1@otenet.gr

Rheumatology International
|June 20, 2007
PubMed

Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.

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