[Complete heart block and Lyme disease: report of two different cases and literature review]
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Updated: Jul 14, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Waldemar Elikowski1, Małgorzata Małek, Jan Flieger
1Oddział Chorób Wewnetrznych Szpitala Miejskiego, ZOZ Poznań-Nowe Miasto, ul Szwajcarska 3, 61-285 Poznań, Poland. welikowski@wp.pl
Insights
Lyme disease (LD) can cause heart block, but two cases show varied outcomes. One patient recovered conduction after antibiotics, while another
Area of Science:
- Cardiology
- Infectious Diseases
- Neurology
Background:
- Lyme disease (LD) commonly presents with fluctuating heart block.
- Complete heart block (CHB) in LD is typically reversible.
Observation:
- Two distinct cases of LD with CHB are presented.
- Case 1: A man with delayed LD diagnosis after syncope and pacemaker implantation experienced conduction recovery post-antibiotics.
- Case 2: A woman with fatigue and flu-like symptoms showed CHB unresponsive to antibiotics, suggesting coexisting congenital CHB.
Findings:
- Antibiotic treatment resolved CHB in one LD case.
- CHB persisted in the second LD case, indicating a potential underlying congenital condition.
- Variable clinical courses of cardiac involvement in LD are highlighted.
Implications:
- Highlights the diverse presentations of cardiac Lyme disease.
- Emphasizes the importance of considering coexisting conditions in atypical cases.
- Informs diagnostic and treatment strategies for Lyme carditis.
Abstract:
The most typical manifestation of cardiac involvement in Lyme disease (LD) is a high grade and usually fluctuating heart block, which is generally reversible, even self-limiting. Two cases of LD with a different course of complete heart block (CHB) are described. In a 43-year-old man admitted due to episodes of syncope, the diagnosis of LD was delayed -- after pacemaker implantation -- when he developed joint and neurological symptoms. Following ceftriaxone treatment atrioventricular conduction returned to normal. In the second case of a 26-year-old woman, presenting on admission with fatigue and flu-like symptoms, ECG showed CHB with a stable escape rhythm of about 52/min. Unlike the first case, she could recall neither a tick bite nor skin rash, but epidemiological history and serologic test results were indicative of LD. In this case, antibiotic therapy did not influence atrioventricular block, which was well tolerated. This suggested the coexistence of borreliosis and previously unrecognised congenital CHB.
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