Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Should Patients With Ocular Myasthenia Gravis Be Started on Immunosuppression to Prevent Generalization?

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2026
Same author

Between a Chiasm and a Hard Place.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2026
Same author

Optic Atrophy in Wolfram Syndrome Type 1: A Retrospective Analysis of Visual Outcomes and Biomarker Correlates.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2026
Same author

Reversible Cortical Visual Symptoms of Hyperosmolar Hyperglycemic State May Occur in Patients with Borderline Serum Osmolality.

Neuro-ophthalmology (Aeolus Press)·2026
Same author

Persistence of pulsatile tinnitus in patients with idiopathic intracranial hypertension following resolution of papilledema: Response.

Journal of the neurological sciences·2026
Same author

Visual outcomes in a series of patients with papilledema and comorbid nutritional deficiency.

Frontiers in ophthalmology·2026

Related Experiment Video

Updated: Jul 14, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Optic disc edema.

Gregory P Van Stavern1

  • 1Department of Ophthalmology, Neurology, and Neurosurgery, Wayne State University, Detroit, Michigan, USA.

Seminars in Neurology
|June 20, 2007
PubMed
Summary

Optic disc edema has various causes, ranging from benign to severe. Differentiating these requires careful examination, as papilledema indicates elevated intracranial pressure, guiding appropriate treatment.

Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Optic disc edema results from diverse pathological processes with potential visual and neurological impacts.
  • Accurate diagnosis is crucial for effective management and preventing adverse outcomes.

Purpose of the Study:

  • To highlight the importance of distinguishing various causes of optic disc edema.
  • To emphasize the role of clinical examination in identifying papilledema and other etiologies.

Main Methods:

  • Review of clinical features differentiating optic disc edema.
  • Emphasis on thorough patient history and comprehensive eye examinations.
  • Discussion of the underlying pathogenesis of disc swelling.

Main Results:

  • Papilledema, indicative of elevated intracranial pressure, presents distinct clinical features.

More Related Videos

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

Related Experiment Videos

Last Updated: Jul 14, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

  • Congenital anomalies of the optic disc can mimic edema, necessitating careful recognition.
  • Axoplasmic transport backflow is the proposed ultimate mechanism for disc swelling.

    • Conclusions:

    • Differentiating optic disc edema etiologies is essential for appropriate patient care.
    • Clinical assessment is key to distinguishing papilledema and avoiding unnecessary investigations for anomalous discs.
    • Treatment strategies for optic disc edema are dictated by the underlying cause.