Related Experiment Video
Updated: Jul 14, 2026

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
[Regular aerobic physical activity improves the lipid profile in persons with excessive body weight]
Z Stránská1, M Matoulek, P Fábin
1III. interní klinika 1. lékarské fakulty UK a VFN Praha. zuzana.stranska@seznam.cz
Unlabelled:
A review of physical activity-induced lipid changes is presented. The review was compared with results we obtained in a reconditioning program involving 25 untrained obese patients who attended the reconditioning centre of the 1st Faculty of Medicine of Charles University for three months. A significant decrease was found in both HDL-cholesterol, triglycerides and the atherosclerosis index. No significant changes were recorded in the total and LDL-cholesterol level.
Conclusion:
Aerobic physical activity can induce changes in lipid levels in overweight and obese patients. Indication of regular aerobic physical activity should not be omitted in current practice.
Related Concept Videos
Atherosclerosis III: Management
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Cholesterol: Significance and Regulation
Considering cholesterol and...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion