Multi-centered clinical study on effects of nano-amomi paste in treating children's anorexia

Min Wu1, Zhan Li, Jian-Er Yu

  • 1Department of Traditional Chinese Medicine, Affiliated Xinhua Hospital of Medical College of Shanghai Jiaotong University, Shanghai 200092. minwu@eastday.com

Insights

Nano-Amoni Paste (nmAP) effectively treats children's anorexia (AR) with no adverse reactions. This study confirms nmAP as a safe and beneficial option for pediatric AR management.

Area of Science:

  • Pediatric Gastroenterology
  • Traditional Chinese Medicine
  • Pharmacology

Background:

  • Children's anorexia (AR) presents a significant clinical challenge.
  • Current treatment options for pediatric AR require further investigation for efficacy and safety.

Purpose of the Study:

  • To evaluate the therapeutic effect and safety of nano-Amoni Paste (nmAP) for children diagnosed with anorexia.
  • To compare nmAP's efficacy against established control treatments in a pediatric population.

Main Methods:

  • A randomized, double-blinded, parallel-controlled trial was conducted with 180 pediatric patients diagnosed with AR.
  • Patients were divided into three groups: nmAP treatment, positive control, and negative control.
  • Treatment involved topical application of nmAP or placebo paste combined with oral liquids over two 10-day courses.

Main Results:

  • The nmAP group demonstrated high total effective rates (85.0%) and cardinal symptom effective rates (95.0%).
  • Significant improvements were observed in food intake, appetite, complexion, and reduced restlessness across all groups (P<0.05).
  • No adverse reactions were reported in any treatment group, indicating a favorable safety profile.

Conclusions:

  • Nano-Amoni Paste (nmAP) is a safe and effective therapeutic agent for treating children's anorexia.
  • The findings support the use of nmAP as a viable treatment option for pediatric AR.
Abstract

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