Related Experiment Video
Updated: Jul 14, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Returned medicines: waste or a wasted opportunity?
Adam J Mackridge1, John F Marriott
1Pharmacy Practice Research Group, School of Pharmacy and Chemistry, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK. a.mackridge@ljmu.ac.uk
Many unused medicines returned by patients are suitable for re-use, presenting a valuable resource. Reconsidering medicine re-use policies could benefit both developing countries and the UK.
Area of Science:
- Pharmacoeconomics
- Public Health
- Pharmaceutical Policy
Background:
- Current UK policy prohibits the re-use of returned medicines, leading to their destruction.
- Previous research indicates a significant proportion of returned medicines remain suitable for re-use.
Purpose of the Study:
- To assess the quantity, type, and suitability for re-use of medicines returned to community pharmacies and GP surgeries.
- To evaluate the financial value and potential for re-use of these returned medicines.
Main Methods:
- A two-month audit of returned medicines from participating pharmacies and GP surgeries in Eastern Birmingham PCT.
- Assessment of returned medicine packs by a registered pharmacist against predefined suitability criteria.
Main Results:
- Over 3765 medicine items worth £33,608 were returned.
- Cardiovascular and Central Nervous System (CNS) drugs were the most common returns.
- One-quarter of returned medicine packs (1248/4291) were suitable for re-use, with many containing essential medications.
Conclusions:
- Substantial quantities of unused medicines with significant financial value are returned.
- A considerable portion of these returned medicines are suitable for re-use.
- The study supports reopening the debate on medicine re-use, particularly for resource-limited settings and within the UK.
Related Concept Videos
Pharmaceutical Poisoning: Potential Scenarios
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence
Pharmaceutical Poisoning: Treatment Strategies
Drug Regulation