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Related Concept Videos

Sample Handling01:02

Sample Handling

Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
Key Techniques in Microbiology01:19

Key Techniques in Microbiology

Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Standard Precaution01:26

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

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Related Experiment Video

Updated: Jul 14, 2026

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices
08:53

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices

Published on: October 3, 2016

How can we make laboratory testing safer?

D Joe Boone1

  • 1Division of Laboratory Systems, National Center for Preparedness, Detection, and Control of Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. dboone@cdc.gov

Clinical Chemistry and Laboratory Medicine
|June 21, 2007
PubMed
Summary

Laboratory testing errors can lead to diagnostic errors, impacting patient safety. Collaboration between users, payers, and laboratories is crucial to reduce these errors and improve healthcare outcomes.

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Last Updated: Jul 14, 2026

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Area of Science:

  • Laboratory Medicine
  • Patient Safety
  • Healthcare Quality

Background:

  • Diagnostic errors in laboratory medicine stem from delayed or incorrect diagnoses, underutilization of tests, or use of outdated methods.
  • Laboratory test results are critical for physician decision-making, necessitating an understanding of error frequency, patient harm, and points of failure.
  • Errors in laboratory testing can significantly impact patient care and outcomes.

Purpose of the Study:

  • To explore strategies for reducing laboratory testing errors.
  • To enhance patient safety through improved laboratory practices.
  • To foster collaboration among laboratory service providers, users, and payers.

Main Methods:

  • Convened the US Quality Institute Conference (2003) and the Institute for Quality in Laboratory Medicine (2005).
  • Brought together stakeholders including providers, users, and payers of laboratory services.
  • Focused on collaborative approaches to minimize errors and improve safety.

Main Results:

  • Partnerships between laboratory service users and payers are essential for error reduction.
  • Integration with laboratory information systems can aid in test ordering, patient preparation, and interpretation.
  • Quality assessment must expand to include non-analytical errors.

Conclusions:

  • Users and payers must actively partner with laboratories to enhance patient safety.
  • Laboratory information systems should support clinical decisions regarding testing.
  • A universal culture of safety, implemented organization-wide, is vital for healthcare institutions.