Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory evoked potentials in the Japanese monkey.

T Kamada1, K Kameda, S Kojima

  • 1Department of Oral Physiology, Hokkaido University School of Dentistry, Aichi, Japan.

Journal of Medical Primatology
|August 1, 1991
PubMed
Summary

Japanese monkeys showed auditory sensitivity loss at 4-6 kHz in peripheral systems. However, auditory brain stem response (ABR) indicated increased sensitivity at 8 kHz, suggesting central nervous system involvement.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of Human Monoclonal Antibodies for Analaysis of Human Sperm Antigens.

Development, growth & differentiation·2023
Same author

Persistence of recipient-derived as well as donor-derived clones of cytomegalovirus pp65-specific cytotoxic T cells long after allogeneic hematopoietic stem cell transplantation.

Transplant infectious disease : an official journal of the Transplantation Society·2014
Same author

Intracranial dural arteriovenous fistula with retrograde cortical venous drainage: use of susceptibility-weighted imaging in combination with dynamic susceptibility contrast imaging.

AJNR. American journal of neuroradiology·2010
Same author

Hematopoietic stem cells prevent hair cell death after transient cochlear ischemia through paracrine effects.

Neuroscience·2007
Same author

Intracranial dural arteriovenous fistulas with retrograde cortical venous drainage: assessment with cerebral blood volume by dynamic susceptibility contrast magnetic resonance imaging.

AJNR. American journal of neuroradiology·2006
Same author

Umpolung of vinyloxiranes: regio- and stereoselectivity of the In/Pd-mediated allylation of carbonyl compounds.

The Journal of organic chemistry·2001

Area of Science:

  • Neuroscience
  • Auditory Neuroscience
  • Animal Models

Background:

  • Auditory sensitivity is crucial for communication and survival.
  • Understanding the peripheral and central mechanisms of hearing loss is vital.
  • Japanese monkeys serve as a relevant model for human auditory research.

Purpose of the Study:

  • To compare auditory sensitivity measurements using electrophysiological and behavioral methods in Japanese monkeys.
  • To investigate the origin of auditory sensitivity changes at different frequencies.
  • To differentiate between peripheral and central auditory processing in response to auditory stimuli.

Main Methods:

  • Auditory sensitivity was assessed using auditory brain stem response (ABR), whole nerve action potential (AP), and cochlear microphonics (CM).

Related Experiment Videos

  • Tone bursts ranging from 0.5 to 8 kHz were used for auditory stimulation.
  • Results were compared with behavioral audiometry data.

    • Main Results:

    • A decline in auditory sensitivity was observed at 4-6 kHz across electrophysiological measures (AP, CM).
    • An increase in auditory sensitivity specifically at 8 kHz was detected solely through ABR.
    • These findings suggest frequency-dependent origins for auditory sensitivity alterations.

    Conclusions:

    • The observed sensitivity loss at 4-6 kHz appears to originate in the peripheral auditory system.
    • The increased sensitivity at 8 kHz, evident only in ABR, indicates a central nervous system component.
    • This study highlights the utility of combining different auditory assessment methods to pinpoint the location of auditory processing deficits.