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Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation IV: Nursing Management01:17

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A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...

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Updated: Jul 14, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Infrarenal aortic devices: failure modes and unmet needs.

W Anthony Lee1

  • 1Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, FL 32610-0286, USA. leewa@surgery.ufl.edu

Seminars in Vascular Surgery
|June 21, 2007
PubMed
Summary

Endovascular repair of abdominal aortic aneurysms is standard care but requires lifelong monitoring due to device failures. Understanding these complications is key to improving future treatments.

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Area of Science:

  • Vascular Surgery
  • Medical Device Technology
  • Biomedical Engineering

Background:

  • Endovascular aneurysm repair (EVAR) is a standard treatment for abdominal aortic aneurysms (AAA) in suitable patients.
  • Since 1991, numerous EVAR devices have been developed, trialed, and used clinically.
  • Four main EVAR devices are currently available commercially.

Purpose of the Study:

  • To review the late failures and complications associated with current endovascular abdominal aortic aneurysm repair devices.
  • To identify device-specific and therapy-related failure modes.
  • To highlight unmet needs and suggest future directions for EVAR technology improvement.

Main Methods:

  • Review of literature and postmarket data on endovascular abdominal aortic aneurysm repair devices.
  • Analysis of reported failure modes and complications.
  • Categorization of failures into device-specific and therapy-related.

Main Results:

  • All commercially available EVAR devices are associated with late failures and complications.
  • Failure modes vary, with some being inherent to the endovascular approach and others specific to device design.
  • Diligent postoperative surveillance is essential for all patients undergoing EVAR.

Conclusions:

  • Despite advancements, current EVAR devices are not free from late complications.
  • Identifying specific failure modes is crucial for guiding the development of more durable and reliable EVAR technologies.
  • Further research and innovation are needed to address the unmet needs in endovascular abdominal aortic aneurysm repair.