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[Neonatal outcome in pregnancies complicated with pregestational diabetes mellitus]

Aleksandar Cetković1, Marina Durović

  • 1Klinicki centar Srbije, Institut za ginekologiju i akuserstvo, Beograd. vlatka.c@yubc.net

Vojnosanitetski Pregled
|June 22, 2007
PubMed

Insights

Pregnancy with pregestational diabetes mellitus (PGDM) significantly increases the risk of neonatal complications, including macrosomia, birth injuries, and congenital malformations. Optimal maternal glucose control before and during pregnancy is crucial for reducing adverse neonatal outcomes.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Endocrinology

Context:

  • Pregestational diabetes mellitus (PGDM) is associated with elevated risks of maternal and neonatal complications.
  • Understanding neonatal outcomes in PGDM pregnancies is critical for improving perinatal care.

Purpose:

  • To determine neonatal outcomes in pregnancies complicated by pregestational diabetes mellitus.
  • To identify factors influencing neonatal outcomes in women with PGDM.

Summary:

  • Women with PGDM experienced significantly higher rates of neonatal complications (85%) compared to the control group (15.5%).
  • Specific complications included macrosomia, birth injuries, neonatal deaths, and congenital malformations, all more frequent in the PGDM group.
  • A strong correlation was found between maternal glycemic control and neonatal outcomes.

Impact:

  • Highlights the increased incidence of neonatal morbidity and mortality in PGDM pregnancies.
  • Emphasizes the importance of preconception and prenatal glucose management for reducing neonatal complications in women with PGDM.
Abstract

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