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Updated: Jul 14, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Malignant melanoma of the sinonasal mucosa: two case reports and a review
Alicia R Sanderson1, Brendan Gaylis
1Department of Otolaryngology, Naval Medical Center, San Diego, CA 92134-1005, USA. arsanderson@nmcsd.med.navy.mil
Abstract:
Malignant melanoma of the sinonasal cavity is an uncommon disease, and therefore a limited amount of data exists regarding its optimal treatment. The course of the disease is highly variable. Individual survival is also highly variable, but the overall prognosis is poor; probably because patients generally present at a late stage and because the disease has a proclivity for distant dissemination. We describe 2 recent cases of primary malignant melanoma of the sinonasal mucosa, and we review the literature.