Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants

Guirong Wang1, Catherine Myers, Anatoly Mikerov

  • 1Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.

Biochemistry
|June 22, 2007
PubMed

Related Concept Videos

Properties of Continuous Functions01:29

Properties of Continuous Functions

Continuous functions exhibit smooth, uninterrupted behavior, and combining them through standard operations retains this continuity. If f and g are continuous at a point a, then the functions f+g, f-g, cf (where c is a constant), fg, and fg (provided g(a)a) are also continuous at a. This allows the construction of complex functions from simpler continuous parts without losing smoothness.Polynomials, which are expressions formed by sums of powers of x with constant coefficients, are continuous...
191
Histone Variants at the Centromere02:30

Histone Variants at the Centromere

Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...
5.1K
Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
14.8K
Structural Protein Function01:56

Structural Protein Function

Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
30.0K
Structural Protein Function01:56

Structural Protein Function

No description available
3.3K