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Updated: Jul 14, 2026

A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses
Published on: November 4, 2025
Seroreactivity to Pf 155/RESA in two malaria endemic ecological zones in Southern Ghana
1'Noguchi Memorial Institute for Medical Research, Box 25, Legon Ghana. Telephone: (233) 21 500374; Fax: (233) 21 502 182;
Abstract:
Seroepidemiological data are becoming important tools in determining transmission patterns of malaria. We have undertaken a study in 2 different ecological zones in southern Ghana during both the dry and wet seasons. Virtually all the subjects studied were positive to the crude parasite antigen (92%), with majority showing high titres in both areas. Whilst there was a statistical difference in Geometrical Mean Titre (GMT) between the two areas, seasonal variation was not seen. Antibody levels to the Pfl55/RESA and its repeat pepetide (EENV)6 increased progres notsively with age in endemic areas. These findings have relevance in determining malaria transmission in endemic areas.
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