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Quantifying the Cytotoxicity of Staphylococcus aureus Against Human Polymorphonuclear Leukocytes
Published on: January 3, 2020
The bactericidal effect of normal human serum samples from various blood groups against local isolates of
C L Obi1, L I Ahamiojie, R N Ndip
1Department of microbiology, Edo State University, Ekpoma, Edo State.
Abstract:
The sensitivity of staphylococcus aureus isolated in Ekpoma, Edo State, Nigeria, to the bactericidal activity of normal human sera from different blood groups ("A", "B", "AB", "O") was determined using the microtitre plate method. Results obtained revealed that S. aureus was sensitive to pooled serum samples of blood groups "B", "AB", and "O", each accounting for 60.7 per cent, 50.5 per cent and 53.5 per cent respectively, but resistant to blood group "A" with a sensitivity value of 43.3 per cent. This finding which is of clinical importance shows the differences of serum batctericidal activity of normal human sera from different blood group against S. aureus.
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