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Updated: Aug 11, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
[A case of cardiac lipoma in the ventricular septum]
1Department of Thoracic Surgery, Japanese Red Cross, Nagoya First Hospital.
Insights
A large cardiac lipoma in the ventricular septum was successfully resected in a 45-year-old man. This rare case highlights diagnostic imaging and surgical management of cardiac tumors.
Area of Science:
- Cardiology
- Cardiac Surgery
- Diagnostic Imaging
Background:
- Cardiac lipomas are rare, benign tumors originating from mature adipose tissue.
- Symptomatic cardiac lipomas can cause significant hemodynamic compromise.
Observation:
- A 45-year-old male presented with a systolic murmur, leading to the discovery of a large ventricular septal mass.
- Imaging studies including echocardiography, CT, and MRI confirmed a cardiac lipoma with specific attenuation and signal characteristics.
- The mass caused a pressure gradient and bulged into the right ventricle.
Findings:
- Surgical resection via cardiopulmonary bypass was performed, yielding a 6.5 cm yellow, soft tumor.
- Histological examination confirmed mature fatty tissue within myocardial fibers.
- Post-operative complications included ventricular septal split and left-to-right shunt, managed with primary closure and patch reinforcement.
Implications:
- This case underscores the importance of advanced imaging in diagnosing cardiac lipomas.
- Successful surgical management is feasible for symptomatic ventricular septal lipomas.
- Postoperative conduction abnormalities, such as left axis deviation and right bundle branch block, can occur due to surgical manipulation.
Abstract:
A 45-year-old man was admitted because of systolic murmur after routine medical checking. Echocardiography and cardiac catheterization revealed a large mass in the ventricular septum which bulged into right ventricular cavity with pressure gradient of 29 mmHg. The diagnosis of cardiac lipoma was made by CT scanning which showed the mass with attenuation values of -94 Hounsfield units. MR imaging demonstrated the mass with high signal intensity which corresponded to that of subcutaneous fatty tissue. The tumor was resected through the right ventricular incision with the use of cardiopulmonary bypass. It was yellow, elastic soft, sized 6.5 x 4.3 x 3.5 cm, and weighed 44.7 g. On histological examination, the tumor was composed of mature fatty tissues contained with myocardial fibers. After operation, he had split of the ventricular septum, which was closed primarily after removal of the lipoma, and left-to-right shunt. Patch reinforcement was performed at the right ventricular side of the septum on the postoperative 18th day. Postoperative electrocardiogram showed left axis deviation and complete right bundle branch block. This finding seems to be resulted from injury to the anterior branch of left bundle. The postoperative course was uneventful. This patient is the second case of removal of cardiac lipoma in the ventricular septum on review of the literature in Japan.
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