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Updated: Jul 14, 2026

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
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Published on: July 8, 2012

Cdc42: a signal coordinator in hematopoietic stem cell maintenance

Linda Yang1, Yi Zheng

  • 1Division of Experimental Hematology, Children's Hospital Research Foundation, University of Cincinnati, Cincinnati, Ohio 45229, USA.

Cell Cycle (Georgetown, Tex.)
|June 22, 2007
PubMed
Summary

Adult hematopoietic stem cells (HSCs) maintain quiescence in the bone marrow niche. Cdc42 protein is crucial for HSC cell cycle regulation and maintaining their niche residency, ensuring long-term self-renewal and differentiation.

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