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Acinic cell adenocarcinoma of the parotid gland: case-report
Rosa Giannatiempo1, Arianna Monticelli, Francesco Fiorentino
1Dipartimento di Scienze Biomorfologiche e Funzionali, Sezione di Anatomia Patologica e Citopatologia, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, Napoli, Italia.
Abstract:
We report a case of acinic cell adenocarcinoma of the parotid in a 18-year-old young man. Clinical examination showed a firm mobile mass of the gland. Light microscopy revealed the tumor composed of two distinct cell populations: a main one with large, polyhedrical or round cells with eosinophilic cytoplasm and a smaller proportion of granular cytoplasm clear cells. These tumor cells were periodic acid Schiff reaction (PAS) and mucicarmine staining negative. Immunohistochemically tumor main cells exhibited diffuse positive reactivity for cytokeratin and focal for S-100 protein. Both reactions were negative in smaller cell population. Was formulated a diagnosis of "non-specific glandular cell-type of acinic cell adenocarcinoma.