[Phytochemical investigation on Lysimachia fortunei].

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Organic Chemistry

Background:

• Lysimachia fortunei is a plant with traditional medicinal uses.
• Investigating its chemical constituents can reveal novel bioactive compounds.
• Understanding the chemical profile is crucial for pharmacological research.

Purpose of the Study:

• To isolate and identify the chemical constituents present in the ethyl acetate extract of Lysimachia fortunei.
• To contribute to the phytochemical knowledge of the Lysimachia genus.

Main Methods:

• Extraction of compounds from Lysimachia fortunei using ethyl acetate.
• Isolation of compounds via silica gel column chromatography.
• Structure elucidation using Nuclear Magnetic Resonance (NMR) spectroscopy and literature data.

Main Results:

• Nine natural compounds were successfully isolated and identified.
• Identified compounds include: 9,19-cyclolanost-24-en-3-one (1), 24-ethyl-5alpha-cholesta-7, 22(E)-dien-3-one (2), 1-pentatriacontanol (3), beta-stigmasterol (4), 24-ethyl-5alpha-cholesta-7, 22(E)-dien-3beta-ol (5), palmitic acid (6), isorhamnetin (7), kaempferol (8), and quercetin (9).

Conclusions:

• All nine identified compounds represent novel phytochemical findings for Lysimachia fortunei.
• Compounds 1, 2, and 5 are reported for the first time within the Lysimachia genus.
• This research expands the understanding of Lysimachia fortunei's chemical diversity.