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Updated: Jul 14, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
[The contribution of perfusion CT in stroke]
Leonor Lopes1, Rita Sousa, Joana Ruivo
1Serviço de Imagiologia Neurológica, Hospital de Santa Maria, Lisboa, Portugal.
Acta Medica Portuguesa
|June 23, 2007
Summary
Multisection computed tomography (MSCT) and Perfusion CT (PCT) enhance acute stroke imaging. PCT provides functional hemodynamic maps to differentiate reversible and irreversible brain damage, guiding therapy.
Area of Science:
- Neuroradiology
- Medical Imaging
- Neurology
Background:
- Multisection computed tomography (MSCT) advanced neuroimaging, especially for acute stroke detection.
- Traditional non-enhanced CT identified early stroke signs and excluded hemorrhage or non-vascular causes.
- Perfusion CT (PCT) enables functional assessment of cerebral hemodynamics post-contrast injection.
Observation:
- PCT utilizes multi-voxel analysis of time-attenuation curves.
- This analysis generates color maps detailing Cerebral Blood Flow (CBF), Mean Transit Time (MTT), and Cerebral Blood Volume (CBV).
Findings:
- Specific hemodynamic patterns observed in PCT allow differentiation between irreversible and reversible brain damage.
- Identification of 'tissue at risk' is crucial for selecting appropriate acute stroke therapies.
Implications:
- PCT is essential for optimizing acute stroke treatment strategies.
- The study discusses data acquisition, post-processing, and interpretation of PCT findings using clinical examples.
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