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Published on: January 19, 2024
[Intake of an iron-supplemented milk formula as a preventive measure to avoid low iron status in 1-3 year-olds]
J Maldonado Lozano1, L Baró, M C Ramírez-Tortosa
1Departmento de Pediatría, Facultad de Medicina, Universidad de Granada, España. jmaldon@ugr.es
Insights
Iron-fortified toddler formula effectively maintains iron status in young children compared to cow's milk over four months. This study highlights the benefits of iron supplementation for infant nutrition.
Area of Science:
- Pediatric Nutrition
- Hematology
- Nutritional Biochemistry
Context:
- Low iron status is a significant risk factor for iron deficiency anemia in young children.
- Optimal iron intake is crucial for healthy growth and development during early childhood.
Purpose:
- To evaluate the impact of an iron-fortified toddler formula on the iron status of children aged 1-3 years.
- To compare the efficacy of iron-fortified formula versus unmodified cow's milk in maintaining iron nutritional status.
Summary:
- A 4-month double-blind study randomized 33 healthy children to receive either iron-fortified toddler formula or cow's milk.
- While initial hemoglobin and hematocrit were lower in the formula group, these normalized by study end.
- The iron-fortified formula group exhibited significantly higher serum ferritin and lower transferrin levels post-intervention.
Impact:
- Iron-fortified toddler formula is more effective than cow's milk in preserving iron nutritional status in 1-3 year olds.
- Findings support the use of iron-supplemented formulas to prevent iron deficiency in toddlers.
- This research contributes to understanding nutritional strategies for preventing anemia in early childhood.
Objective:
Low iron status is a well known risk factor for iron deficiency anemia in infants and young children. The aim of the present study was to evaluate the influence of an iron-fortified toddler formula on iron status in 1-3 year-olds.
Patients And Methods:
Thirty-three healthy infants and young children were assigned to two groups that received 500 mL/day of and iron-fortified toddler formula or 500 mL/day of unmodified cow's milk for 4 months. Allocation was random and double-blind. Daily dietary intake was calculated by dietary evaluation, and iron nutritional status was assessed (hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, serum iron, ferritin, and transferrin).
Results:
At enrollment, no anemia was found in either group, although hemoglobin concentration and hematocrit were significantly lower in the toddler formula group than in the unmodified cow's milk group. However, these differences disappeared at the end of the intervention period. After 4 months, the toddler formula group showed significantly higher serum ferritin and lower serum transferrin concentrations than the cow's milk group.
Conclusion:
Intake of iron-supplemented toddler formula for 4 months in 1-3 year-olds is more effective in maintaining iron nutritional status than cow's milk.
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