Related Experiment Video
Updated: Jul 14, 2026
08:05
Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
[Bronchial asthma due to storage mite allergy]
R F Kroidl1, U Schwichtenberg, E Frank
1Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenkrankheiten e.V. Rolf.Kroidl@t-online.de
Pneumologie (Stuttgart, Germany)
|June 23, 2007
Summary
Storage mite (SM) allergy in asthma patients is linked to occupational dust exposure, particularly in farmers. Positive RAST and quantitative skin prick tests (QSPT) can predict bronchial provocation test (BPT) outcomes for SM allergy.
Area of Science:
- Allergy and Immunology
- Respiratory Medicine
- Environmental Health
Context:
- Investigates sensitization to storage mites (SM) and house dust mites (HSM) in patients with moderate to severe bronchial asthma.
- Evaluates 90 asthmatic patients through routine skin prick tests, RAST, quantitative skin prick tests (QSPT), and bronchial provocation tests (BPT).
- Correlates allergological findings with domestic and occupational environmental factors.
Purpose:
- To determine the prevalence and occupational links of SM and HSM sensitization in asthmatic patients.
- To assess the predictive value of routine skin tests, RAST, and QSPT for positive BPT results.
- To explore the relationship between environmental exposures and mite allergy in asthma.
Summary:
- A multicenter study found a significant association between SM allergy and occupational dust exposure, especially among farmers, bakers, and wood/paper industry workers.
- While routine skin prick tests were not predictive, positive RAST and QSPT results, particularly for Lepidoglyphus destructor, showed a strong correlation with positive BPT outcomes.
- The study highlights that SM allergy can occur in individuals without direct occupational dust exposure.
Impact:
- Provides insights into the occupational and environmental triggers of SM allergy in asthma patients.
- Suggests that RAST and QSPT are valuable tools for predicting the clinical relevance of SM sensitization.
- Informs diagnostic strategies and potential allergen avoidance measures for asthmatic individuals with mite sensitization.
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