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Published on: August 30, 2018

Endoscopy-related infections and toxic reactions: an international comparison

E Seoane-Vazquez1, R Rodriguez-Monguio, J Visaria

  • 1College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA. pharmacoeconomics@osu.edu

Endoscopy
|June 23, 2007
PubMed

Insights

Most endoscopy-related infections and toxic reactions worldwide between 1974-2004 were preventable. Improving decontamination processes and surveillance systems can significantly reduce patient harm from these events.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Medical Device Safety

Background:

  • Exogenous infections, pseudoinfections, and toxic reactions linked to endoscopic procedures pose a global health risk.
  • These events can lead to significant patient morbidity and healthcare system burden.

Purpose of the Study:

  • To analyze the characteristics of exogenous endoscopy-related infections, pseudoinfections, and toxic reactions reported globally from 1974 to 2004.
  • To identify factors contributing to these adverse events and assess their preventability.

Main Methods:

  • A systematic literature review was performed using Medline and FDA Reports database.
  • Searched for publications between 1966 and 2004, adhering to a prospective protocol.
  • Identified 140 outbreaks reported across 134 scientific articles.

Main Results:

  • Over 94% of the identified outbreaks were preventable.
  • Key contributing factors included inadequate decontamination of endoscopic equipment.
  • A wide range of infections and toxic reactions were documented globally.

Conclusions:

  • Improved decontamination protocols are crucial for preventing endoscopy-related adverse events.
  • Enhancing surveillance systems can aid in early detection and mitigation.
  • Implementing these measures can substantially decrease the clinical burden of these events.

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