Related Experiment Video
Updated: Jul 14, 2026

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships
Published on: April 20, 2022
Going high with preexisting neurological conditions.
Ralf W Baumgartner1, Adrian M Siegel, Peter H Hackett
1Department of Neurology, University Hospital Zürich, Switzerland. ralf.baumgartner@usz.ch
High altitude exposure poses risks for individuals with pre-existing neurological conditions, such as stroke and multiple sclerosis. This review outlines contraindications for travel to high altitudes for various brain disorders.
Area of Science:
- Neurology
- Altitude Medicine
- Travel Medicine
Background:
- High altitude environments present physiological challenges.
- Individuals with pre-existing neurological conditions may be at increased risk.
- Limited data exists on the specific impacts of altitude on these patients.
Purpose of the Study:
- To review the potential impact of high altitude exposure on various pre-existing neurological conditions.
- To provide recommendations on contraindications for high-altitude travel for patients with neurological disorders.
Main Methods:
- Literature review focusing on case reports and pathophysiological considerations.
- Extrapolation of knowledge from low-altitude scenarios.
- Development of absolute and relative contraindications for high-altitude travel.
Main Results:
- Identified neurological conditions include ischemic stroke, cerebral venous thrombosis, multiple sclerosis, and epilepsy.
- New diagnostic and treatment developments are discussed.
- Specific contraindications for high-altitude travel were established for each condition.
Conclusions:
- High altitude exposure requires careful consideration for patients with neurological conditions.
- Recommendations are based on current evidence, emphasizing caution.
- Further research is needed to establish evidence-based guidelines.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Traumatic Brain Injury l: Introduction
Multiple Sclerosis l: Introduction
Seizures ll: Types
