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Related Experiment Videos

BIPASS: BioInformatics Pipeline Alternative Splicing Services.

Zoé Lacroix1, Christophe Legendre, Louiqa Raschid

  • 1Scientific Data Management Laboratory, Arizona State University, PO Box 875706, Tempe, AZ 85287-5706, USA. Zoe.Lacroix@asu.edu

Nucleic Acids Research
|June 23, 2007
PubMed
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BioInformatics Pipeline Alternative Splicing Services (BIPASS) provide scientists with tools for alternative splicing (AS) analysis. BIPASS offers pre-compiled AS data (SpliceDB) and custom analysis of user-submitted sequences (Align&Splice).

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Alternative splicing (AS) is a key mechanism in gene expression regulation.
  • Understanding AS events is crucial for deciphering biological complexity and disease mechanisms.
  • Existing tools for AS analysis vary in accessibility and data integration.

Purpose of the Study:

  • To introduce the BioInformatics Pipeline Alternative Splicing Services (BIPASS).
  • To provide scientists with accessible resources for alternative splicing data exploration and analysis.
  • To offer both pre-computed and custom AS analysis functionalities.

Main Methods:

  • BIPASS comprises two main services: BIPAS-SpliceDB and BIPAS-Align&Splice.
  • BIPAS-SpliceDB offers a data warehouse of a priori extracted AS information from public databases.

Related Experiment Videos

  • BIPAS-Align&Splice enables users to submit their own sequences and genomes for custom AS analysis.

    • Main Results:

    • BIPASS services provide user-friendly navigation of AS results at cluster and sequence levels.
    • Results are presented in downloadable graphs and tables (XML or text format).
    • Both SpliceDB and Align&Splice services are accessible online.

    Conclusions:

    • BIPASS enhances the study of alternative splicing by offering integrated and flexible analysis tools.
    • The services facilitate data retrieval and custom computation for a wide range of scientific inquiries.
    • BIPASS empowers researchers to explore and analyze alternative splicing events more effectively.