Related Experiment Video
Updated: Jul 14, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
[Obesity--a global public health problem]
Roman Urek1, Marija Crncević-Urek, Mirjana Cubrilo-Turek
1Zavod za kardiovaskularne bolesti, Klinika za unutarnje bolesti, Medicinski fakultet, Sveuciliste u Zagrebu, Hrvatska.
Insights
Obesity is a major risk factor for serious health issues like diabetes and heart disease. Effective weight management through diet and exercise is crucial for cardiovascular health and preventing disease progression.
Area of Science:
- Public Health
- Cardiology
- Endocrinology
Background:
- Obesity and overweight are significant components of metabolic syndrome.
- They are established risk factors for numerous chronic diseases, including diabetes, hypertension, coronary heart disease, and certain cancers.
- Cardiovascular disease is the primary cause of mortality in industrialized nations, accounting for 40% of deaths.
Purpose of the Study:
- To highlight the critical role of obesity in metabolic disorders and cardiovascular disease.
- To emphasize the underrecognition and undertreatment of obesity in cardiovascular disease secondary prevention.
- To stress the necessity of lifestyle modifications for managing obesity and reducing cardiovascular disease incidence.
Main Methods:
- Review of existing literature on obesity, metabolic syndrome, and cardiovascular disease.
- Analysis of the relationship between body mass index, abdominal obesity, and health outcomes.
- Discussion of current strategies for obesity management and prevention.
Main Results:
- Obesity, particularly abdominal obesity, is linked to insulin resistance, type 2 diabetes, and coronary artery disease.
- While obesity increases mortality in the general population, a paradoxical association with improved survival in heart failure has been noted.
- Obesity is frequently underdiagnosed and undertreated in patients with existing cardiovascular diseases.
Conclusions:
- Weight loss and prevention of weight gain are paramount strategies for reducing cardiovascular disease incidence.
- Increased physical activity and appropriate dietary interventions are fundamental to obesity treatment.
- There is an urgent need to enhance healthcare professionals' understanding and management of obesity, especially in regions with high prevalence like Croatia.
Abstract:
Obesity and overweight, as a part of the metabolic syndrome, are well known risk factors for the development of diabetes, hypertension, coronary heart disease, hyperlipidemia, stroke, sleep apnea syndrome, osteoarthritis and certain forms of cancer. Cardiovascular disease remains the leading killer in industrialized countries, where it accounts for 40% of deaths. Obesity is defined either by increased waist circumference, waist to hip ratio, or body mass index. Obesity results from an interaction of genes and lifestyle. As people in both developed and developing countries eat more and more energy dense food, and have ever less physical activity, the number of overweight and obese people increases to epidemic proportions. Abdominal obesity plays a key role in the pathophysiology of metabolic disorders, is associated with insulin resistance, and predicts the development of type 2 diabetes and subsequent coronary artery disease. In the general population, obesity is associated with an increased mortality, but paradoxically, a positive correlation between body mass index and survival in congestive heart failure has been reported. In secondary prevention, obesity is underrecognized, underdiagnosed and undertreated in persons with cardiovascular diseases. Weight loss and prevention of weight gain have to be considered one of the most important strategies to reduce the incidence of cardiovascular disease. Increased physical activity and appropriate diet are the cornestones of treatment. Considering the high prevalence of overweight and obesity in Croatia, there is urgent necessity to improve the level of knowledge and skills in understanding obesity by health care services, and to implement appropriate professional strategy to achieve the desired lifestyle modifications.
Related Concept Videos
Obesity
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Stress Prevention and Stress Management Techniques IV
Binge Eating Disorders
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
