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Pediatric intraoperative floppy-iris syndrome
M Edward Wilson1, Rupal H Trivedi, Susannah Mistr
1Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA. wilsonme@musc.edu
Insights
Epinephrine in irrigating solution prevented intraoperative floppy-iris syndrome (IFIS) during pediatric cataract surgery. This finding underscores the importance of epinephrine for preventing IFIS in infants.
Area of Science:
- Ophthalmology
- Pediatric Surgery
Background:
- Congenital cataracts require surgical intervention in infants.
- Intraoperative floppy-iris syndrome (IFIS) is a known complication during cataract surgery.
Observation:
- A 4-month-old infant underwent bilateral congenital cataract removal.
- IFIS signs, including iris floppiness and prolapse, occurred in the left eye but not the right.
- Epinephrine was omitted from the left eye's irrigating solution but used in the right.
Findings:
- Intracameral epinephrine in the irrigating solution effectively prevented IFIS in the infant's right eye.
- The omission of epinephrine in the left eye's irrigation correlated with the development of IFIS.
Implications:
- This case highlights the critical role of intracameral epinephrine in preventing IFIS during pediatric cataract surgery.
- Standardizing the use of epinephrine in pediatric cataract surgery irrigation may reduce intraoperative complications.
Abstract:
We report an unusual intraoperative finding in the case of a 4-month-old infant with bilateral congenital cataracts removed within a 1-week period. Surgery in the right eye was uneventful. During removal of the cataract in the left eye, signs of the intraoperative floppy-iris syndrome (IFIS) were observed; ie, iris floppiness, iris prolapse to the incisions, and progressive miosis. The surgical technique was identical in both eyes except that epinephrine was added to the irrigating solution in the right eye but inadvertently omitted in the left-eye surgery. Use of intracameral epinephrine has been documented to prevent IFIS in adult eyes at risk for developing the syndrome. Our case highlights the importance of epinephrine in the irrigating solution in pediatric cataract surgery.
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