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Updated: Jul 14, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
An overview of neonatal and pediatric wound care knowledge and considerations
1Wound Healing, Long Island Jewish Medical Center, Schneider Children's Hospital, New Hyde Park, New York 11040, USA. mbahares@nshs.edu
Insights
Neonatal wound care requires updated evidence-based practices, considering unique skin properties. This review addresses neonatal skin differences and provides recommendations for wound prevention and management in premature infants and children.
Area of Science:
- Neonatal dermatology
- Pediatric wound care
- Evidence-based medicine
Background:
- Neonatal and pediatric wound care knowledge lags behind adult care.
- Current care regimens are often outdated.
- Technological advances in neonatology contrast with wound care knowledge gaps.
Purpose of the Study:
- To review the literature on neonatal skin's anatomical and structural differences.
- To provide evidence-based recommendations for neonatal wound prevention and management.
- To highlight research opportunities in pediatric wound care.
Main Methods:
- Literature review focusing on neonatal skin properties (percutaneous absorption, adhesive tolerance).
- Analysis of anatomical and physiological factors influencing wound care.
- Discussion of common neonatal wound types and their management.
Main Results:
- Neonatal skin has unique properties affecting percutaneous absorption and adhesive tolerance.
- Specific recommendations for dressing selection, change procedures, and pain management are provided.
- Common neonatal wounds include epidermal stripping, surgical wounds, and pressure ulcers.
Conclusions:
- Updating neonatal wound care requires understanding unique skin physiology.
- Evidence-based guidelines are crucial for effective prevention and treatment.
- Further research is needed to advance pediatric wound management.
Abstract:
Despite significant technological advances in the care of premature neonates and chronically ill children, the knowledge and evidence base for the management of this population's wound care lag far behind its adult counterpart. Updating antiquated care regimens is an uphill battle. This review of the literature seeks to illuminate key anatomical/structural differences in neonatal skin with particular attention paid to percutaneous absorption and tolerance of adhesives. The article also presents anatomically and physiologically based recommendations for the selection of prevention and treatment modalities, including specific dressing types, appropriate dressing change and securement procedures, and pain management. Commonly encountered wound types (epidermal stripping; surgical wounds; extravasation and thermal injuries; chemical burns; pressure ulcers; diaper dermatitis; and wounds secondary to congenital conditions) are discussed. Opportunities for research abound and are considered.
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