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Related Experiment Video

Updated: Jul 14, 2026

Mouse Models for Graft Arteriosclerosis
07:37

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Published on: May 14, 2013

Infected abdominal aortic grafts.

M Y Al-Shehri1, N V McPhail, G Barber

  • 1Department of Surgery, King Saud University-Abha Branch, College of Medicine, Abha, and Division of Vascular Surgery, Ottawa Civic Hospital, Ottawa Ontario, Canada.

Annals of Saudi Medicine
|July 1, 1994
PubMed
Summary

Graft infection after aortic surgery, including aorto-enteric fistula, led to a 58% mortality rate. Further research into prevention and management of aortic graft infections is crucial.

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Area of Science:

  • Vascular Surgery
  • Infectious Disease in Surgery

Background:

  • Aortic grafts are utilized for conditions like aorto-iliac occlusive disease and abdominal aortic aneurysms.
  • Graft infection is a serious complication following aortic reconstructive surgery.

Purpose of the Study:

  • To analyze the incidence, presentation, and outcomes of aortic graft infections.
  • To evaluate the effectiveness of current treatment strategies for graft infections.

Main Methods:

  • Retrospective review of 1711 patients who received aortic grafts between 1976 and 1986.
  • Analysis of graft infection cases, including presentation (aorto-enteric fistula, groin abscess), treatment (graft excision, extra-anatomic bypass), and outcomes.

Main Results:

  • Twelve cases of graft infection were identified.
  • Six patients presented with aorto-enteric fistula, and six with groin abscesses.
  • Treatment involved graft excision and extra-anatomic bypass, resulting in a 58% mortality rate (7 deaths) and three above-knee amputations.

Conclusions:

  • Aortic graft infections have a high mortality rate, comparable to existing literature.
  • Effective prevention and management strategies for aortic graft infections require ongoing investigation.