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Triiodothyronine modulates thymocyte migration

M M Ribeiro-Carvalho1, K R F Lima-Quaresma1, T Mouço1

  • 1Laboratory on Thymus Research, Department of Immunology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, BrazilMiguelote Viana Central Laboratory, Niterói, BrazilLaboratory of Inflammation, Department of Physiology and Pharmacodynamics, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil;Department of Histology and Embryology, Biomedical Sciences Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Scandinavian Journal of Immunology
|June 26, 2007
PubMed
Summary

Thyroid hormone triiodothyronine (T3) enhances extracellular matrix (ECM) production in the thymus. This boosts thymocyte migration, crucial for T-cell development.

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